Sunday, I clinched WB US 72 in Tennessee. We drove part of it during the Road Meet, so I decided to drive the whole thing from the Mississippi Line to US 64.
Like all Tennessee US Routes, it's co-signed with a TN State Route (57), but the co-signing seems to alter between Primary and Secondary State Route, often within a couple blocks.
Just beyond TN 385, West 72 is posted as North 72 (Kudos to Cody for the tip off on that one). Of course, the exit ramp from WB 385 to US 72 has (Primary) TN 72 Shields.
The I-240/US 72 interchange is a big mess from all the reconstruction going on.
There are no END signs when 72 reaches East Parkway (US 64/70/79 TN Secondary 212), nor any guide signs along 72 indicating you're at 64. If you don't have a map, or know where you're going you'll get lost. TN 57 appears to turn north and follow 64.
East Parkway at Union, there is a trailblazer for 72/57 which seems to indicate they follow Union. I didn't think to check EB Union approaching Parkway.
As an aside, US 51 and US 61 are well posted, though 78 isn't posted very well from what I saw.
There is no signage along 64/70/79 at Poplar St indicating one turns on US 72.