My sister is moving to State College to take classes in Penn State University. We'll be hauling a trailer, so the route you guys suggest should be the least mountainous as possible.
Our route (if we are driving) will pretty much be I-81 to US 322. It's all freeway, and it shouldn't be too bad in terrain. The only non-freeway segments we'll be on is surface streets and a 1 mile stretch of US 322.
Feel free to suggest routes, and I'll tell them to my dad for us to try.