Highways That are Overal Signed as One Direction, Signed in Another Direction

[kphoger]

US 101 in Washington, in its 3/4-loop around the Olympic Peninsula, goes from being signed N/S to E/W to S/N.

Literally four posts before yours.  ↓

In because US-101 hasn't been mentioned yet.  It changes twice in Washington, to the point that it eventually ends up with North and South completely reversed.  That is, if you head up from Astoria on US-101 North, you'll eventually be on US-101 East, and then ultimately on US-101 South.

[zzcarp]

A couple northern Ontario ones:

Ontario Highway 17 is an east-west highway, but at Sault Ste Marie along the east shore of Lake Superior it is signed north-south until it changes back to east-west somewhere along Superior's north shore.

Ontario Highway 11 changes orientation from north-south to east-west at Cochrane.

Secondary Highway 548 is signed north-south to St. Joseph Island, then it forms a complete loop signed east-west.

As for Colorado, we have Highway 119 that is generally north-south, but is signed as west from its northern terminus at I-25. Admittedly there are few directional signs with the reassurance markers until southwest of Longmont when it is definitely signed north-south the rest of the way.

Then there's Colorado 42 which is signed east-west from US 287 to 96th Street in Louisville, and then it changes to north-south to its northern terminus at Highway 7.

[kirbykart]

US 4 is generally east-west but is signed north-south in New York.

[MATraveler128]

I-287 is mostly signed north-south, but changes to east-west in New York.

[7/8]

Another Ontario example is Highway 28, which is north-south from Highway 7 near Peterborough to Highway 62 in Bancroft, then becomes east-west to Highway 41 in Denbigh.

An interesting note is that for the short concurrency between Highway 28 and 62 in Bancroft, Highway 28 is marked as east in one direction and south in the other. This might be interesting enough for it's own thread.

[KCRoadFan]

I believe US 41 is signed east-west in southern Florida, along the "Tamiami Trail" stretch between Miami and Naples (parallel to Alligator Alley). It used to be called US 94.