US, Interstate routes that cross only once but with no interchange

[ilpt4u]

I-80 and US 6 are multiplexed at the IN/IL Border. That in and of itself should auto-disqualify from this thread

[NWI_Irish96]

I-80 and US 6 are multiplexed at the IN/IL Border. That in and of itself should auto-disqualify from this thread

I can confirm as I look at that point outside my living room window.

[cwf1701]

I-75 and US-12. Access for US-12 from Northbound I-75 is via the interchange with I-96.

[formulanone]

I-95 crosses over US 27 in Miami, no exits.

[roadman65]

US 92 does not intersect I-75 in Tampa.

[Revive 755]

Couple more for Illinois:

* I-57 at US 40
* I-57 and US 150

[paulthemapguy]

I-88 (IL) and US 52 in Dixon

In Illinois, I'll add the pair of I-57 and US150, and the pair of I-280 and US67, though the Airport Road interchange is a close enough connector.  There's also I-57 and US40, but the Fayette Ave interchange is good as a connector.

[Big John]

Minnesota - none
Wisconsin - none

Long distance toll roads:
Minnesota - none
Wisconsin - none

I think I'm seeing a trend here.

Wis 58 crosses I-90/94 with no interchange.

[Roadgeekteen]

Minnesota - none
Wisconsin - none

Long distance toll roads:
Minnesota - none
Wisconsin - none

I think I'm seeing a trend here.

Wis 58 crosses I-90/94 with no interchange.

Not a US route.

[WNYroadgeek]

I believe I-90 & US 11 in Syracuse qualifies.

As does I-90 and US 62 in Hamburg (though they do come close, as both interchange/intersect NY 179 .2 miles from each other.

[jmacswimmer]

In Pennsylvania:
I-70/76 and US 219 qualifies. The Somerset exit is signed for US 219 but it actually uses a collection of state routes to make the connection.

The PA Turnpike has several:
I-76/US 322
I-76/US 222 involves a connecting road
I-76/US 119 involves a connecting road
I-76/US 220 uses Bus US 220 as the connector

Additionally, the PA Turnpike NE Extension has 2:
I-476/US 202
I-476/US 222

[fillup420]

I-40 and US 13

[bassoon1986]

Surprisingly all of Texas interstates intersect all of its US routes. Did not find any there.

In Arkansas: I-49 and US 67 in Texarkana.


iPhone

[epzik8]

I-70 crosses over U.S. 11 in Hagerstown, Maryland with no access. You have to take I-81 north to U.S. 40 east.

[Ben114]

There are none is one, was previously mentioned in MA, but I-95 and US 44 in RI do not have an interchange (unless you count it if it's signed with "to", in this case)

[Roadgeekteen]

There are none in MA, but I-95 and US 44 in RI do not have an interchange (unless you count it if it's signed with "to", in this case)

I-90 and US 7 have no interchange, and it was already mentioned in this thread.

[plain]

...

I'm surprised you didn't mention the one in your own backyard: I-64 & US 58

[sprjus4]

...

I'm surprised you didn't mention the one in your own backyard: I-64 & US 58

Never thought about that one surprisingly for this thread (I looked at US-13 and US-460, but not US-58) but yes they do cross in Norfolk without intersecting.

On the western side, the rather seamless movement from I-64 East to US-58 West and vice versa actually utilizes a segment of I-664, not directly touching I-64.

I-464 crosses US-460 without intersecting, though the OP specified 2dis only.