Not long ago, I was looking at Wheeling on Streetview and I noticed
this and other signs for the left exit from eastbound I-70 onto the US 250 freeway. I'd known about the left exit, but I didn't understand the 16th Street reference: if you were actually going to 16th Street, you'd probably do better to take the Main Street exit rather than passing through the tunnel and approaching from the other side of downtown.
After a bit of research, I found this map from 1976 at
https://www.interstate-guide.com/i-470-wheeling/. It shows
the northern section of the US 250 freeway open all the way to I-70, but with access to I-70 only two and from the
east despite the ramp stubs to and from both west and east being completed along with the tunnel and I-70 itself in
1966 or so. I also found a 1978 USCGS topo at historicaerials.com showing the same configuration, but drawn
unconvincingly in light purple double lines instead of bold solid purple.

That would certainly explain 16th Street as a control, especially from the east.
Also from interstate-guide.com, there's this laughably bad Exxon map:

I also read somewhere that the full US 250 freeway in Wheeling wasn't opened until 1982. I forgot where I found it, though.
So... was there ever a time when the US 250 freeway was connected to I-70 only to and from the east, or was that a topographic brain fart?