Mildly amusing to see a user named "snowc" expressing concern about snow as a reason for calling off a planned trip!
(Not intended to make fun of him—just an amusing coincidence.)
I think when you refuse to drive because it might snow a little bit on a day when you may or may not be driving and the roads you may be driving may or may not be already plowed, you can be poked fun at.
I wouldn't cancel a trip this far out just because it's winter, but I'd definitely keep an eye on the forecast and not go if snow was being predicted.
Nearly 20 years ago I had a work trip to DC planned. At the time I was driving a 4WD truck so I didn't really have any worries. I ran into snow along I-68 in Maryland (surprise) but had no issues. On the way back, I intended to drive I-66 to I-81 to I-64 for a change of pace, but it started snowing not long after I got out of the metro DC area (a stop at the Haymarket Sheetz for gas and breakfast). I know how truckers drive like idiots in the snow, so I bailed off I-81 at VA 55 and used what existed of Corridor H at the time. I was more comfortable climbing the Fore Knobs on WV 42 in a snowfall with decent accumulations than I was a skiff of snow on I-81 with trucks flying by without regard to weather conditions.
Now, I don't have a vehicle that is dependable in snow, so I would definitely not attempt a trip if snow was in the forecast.
And "may or may not be plowed" isn't really anything that can be counted on. I've seen it snow faster than the plows can keep it off.