25 greatest US highways/routes

[Flint1979]

There seems to be a West Coast bias here. The only ones that seem mostly in the eastern part of the United States are the obvious US 1, US 13 that is somehow important only because it is an unlucky number, and somehow US 33 got rerouted on both ends?

33- from Washington DC to Chicago

33 originally went to St. Joseph, Michigan on the west end.

[kkt]

The lost road - the Winnemucca to the Sea highway (former US 299 in CA and former US 140 in NV).

Just for the record, I don't think Nevada route 140 was ever a US highway.

[Bickendan]

The lost road - the Winnemucca to the Sea highway (former US 299 in CA and former US 140 in NV).

Just for the record, I don't think Nevada route 140 was ever a US highway.

Correct, OR/NV 140 never was a US highway. It may have gotten its number with a pipeline dream to make it one (particularly with the Winnemucca to Sea name), but nothing serious came of it.
As it stands, ODOT doesn't officially recognize the Winnemucca to Sea name; OR 140 is known by Lake of the Woods Highway (ORH 270), South Klamath Falls Highway (ORH 424), Klamath Falls-Lakeview Highway (ORH 20), and Warner Highway (ORH 431).