I've long wondered what would be the ideal road trip from west to east (or vice versa) across the Appalachians.
Ideally, the route would stay as true E-W as possible without any significant northward or southward deviations.
Even more ideally, you would stay on the same numbered route the whole way.
I always default to US 50, starting in Cincinnati and working east all the way to the DC area.
I think I-80 from Youngstown to the NYC metro is also a good candidate.
Using various route numbers, KY 100 east from Franklin to Burkesville, then KY 90 to Monticello, KY 92 to Pineville, a short jog south on US 25E, then US 58 all the way across Virginia to at least South Boston.
The idea would be to get a good experience with the geography of the trip. You wouldn't get as much of a feel for the social aspects of the towns you pass through on I-80, but you'd get a better idea on a route like US 50 because the road passes through so many smaller towns.
Anyone else got any ideas or opinions to offer?