The only independently-signed portion of US 48 as it is now planned will be between Bismarck (Mt. Storm Lake) and Moorefield. Everything else will be co-signed with US 33, US 119, US 250, WV 92, US 219, WV 93, WV 55, WV 259 and VA 55.
If you want to put US 48 on the Kentucky parkways, best way to do it is run it concurrently with I-79 and US 19 to Beckley, then replace US 121 with US 48 for the Coalfields Expressway, then co-sign it with US 460 to Watergap, then have it replace KY 80, the Hal Rogers Parkway and the Cumberland Parkway.