I have some photos of some signs that have changed over time.
Here is one in Jasper County, SC in 2009 on NB I-95 at Exit 18.
https://www.flickr.com/photos/54480415@N08/15358789506/in/album-72157648125641151/
Here is the same location in 2021.
https://www.flickr.com/photos/54480415@N08/51819435493/in/album-72157648125641151/
Road 13 is now Bees Creek Road.
I've done a similar then and now on my YouTube channel back in 2020. I may make more of these...
https://youtu.be/N6kWvuUyJXI
This was one of the signs I tried and failed to capture on my previous big road trip.
https://www.flickr.com/photos/54480415@N08/50951020643/in/album-72157648125641151/
Too bad you don't have any images of when the former rest areas south of Exit 18 were opened for all vehicles.
One I did today for CA 49 for the Merced River Canyon in 1963 versus 2019:
https://www.facebook.com/groups/calhighways/permalink/5196458470404872/
It turns out these signs aren't the same; the fading on the shields on this BGS for I-95 for I-595 is probably less than 10 years old:
2011:
(https://live.staticflickr.com/333/19924801955_12ba80f03b_b.jpg) (https://flic.kr/p/wmFPsc)
2022:
(https://live.staticflickr.com/65535/52094012452_75d4ce1eab_b.jpg) (https://flic.kr/p/2nnnqYu)