Cities that have interstates (or US routes) with the same first number

[JCinSummerfield]

Let's here it for Sylvania, OH!  US-23 & US-223!
US-224 & US-250 intersect in the middle of BF, Ohio.

[Charles2]

Atlanta: US 23, 29 & 278; I-285
Columbus, GA: US 278 & 280
Lagrange, GA: US 27 & 29
Nashville: US 41 & 431; I-40
Lexington: US 60, 62 & 68 & I-64; US 25 & 27
Cincinnati: US 42 & I-471
Frankfort, KY: US 421 & 460
Charleston, WV: I-77 & 79
Opelika, AL: US 29 & 280
Sylacauga, AL: US 231 & 280
Pulaski, TN: US 64 & I-65
Paragould, AR: US 49 & 412
Harrison, AR: US 62 & 65
Searcy, AR: US 64 & 67

[JustDrive]

Crescent City, CA:  US 101 and US 199
Sacramento, CA:  I-5 and US 50

[roadman65]

Allentown, PA: US 22 and US 222

Not only do these two start with the same number, but they are all with the digit 2.

[Zzonkmiles]

Minneapolis-St. Paul, MN I-90/94

I-90 goes nowhere near Minneapolis, please check your map.

Oh wow! Epic fail. For whatever reason, I thought I-90 and I-94 split in Minneapolis, but they actually split hundreds of miles east in Wisconsin! Yikes!

But thanks for the correction!

[NWI_Irish96]

Some of these have already been mentioned, but for Indiana:

Indianapolis: US 31/36, I-465/US 40/421, I-65/59, I-70/74
Fort Wayne: US 24/27, US 30/33
Terre Haute: US 40/41
Plymouth: US 30/31
Kokomo: US 31/35
Hammond/Gary/Portage: I-90/94
Remington/Wolcott: US 24/231
Huntington: US 24/224
Decatur: US27/224

[dgolub]

Brewster, NY: I-684 and US 6
Fort Lee, NJ: US 9 and US 9W
Stonington, CT: US 1 and US 1A

[hotdogPi]

Stonington, CT: US 1 and US 1A

Just about every alternate then.

[Charles2]

Pell City, AL: I-20 & US 231
Hamilton, AL & Tupelo, MS: I-22 & US 278
Brooksville, AL: US 231 & US 278

[bugo]

Tulsa: I-44, I-444, US 412; US 64, US 66
Muskogee: US 62, US 64, US 69
Wister: US 270, US 271
Vinita: US 60, 66, 69
DeQueen: US 70, US 71

[iowahighways]

Davenport, IA: US-6, US-61, US-67

If we're counting single digits, Des Moines is served by US 6, 65, and 69.

Others for Iowa:
-Algona: US 18 & US 169
-Ames: US 30 & I-35
-Cedar Rapids: US 30 & I-380
-Council Bluffs: I-29 & US 275
-Osceola: US 34 & I-35
-Sioux City: I-29 & US 20, also US 75 & US 77 (although they intersect in Nebraska)
-Waterloo: US 20 & US 218

[MikeSantNY78]

Minneapolis-St. Paul, MN I-90/94

I-90 splits from I-94 around Tomah, Wisconsin, and runs along extreme southern Minnesota about 90 miles or so south if I-94 (connected to MSP by I-35) - sorry...

[Darkchylde]

I know KC was mentioned upthread, but there's more.

I-49, I-435, I-470, US 40
US 50, US 56
I-29, US 24
I-70, US 71
And counting the outskirts of town (but still within I-435), there's also I-670, I-635 and US 69.

[KG909]

My city Fontana, CA has I-15 and I-10. Also has I-215 a few miles away and future interstate State Route 210.