US routes that don't fit the numbering/direction convention

[dgolub]

"Unlike 2-digit US routes, there was never a guideline stating that 3-digit routes should run in a particular direction -- that is, no stipulation that north/south branch routes should be assigned odd numbers (so as to be considered branches of north/south main routes), and that even numbers should be given to east/west branch routes."

And I'd say US-430 is proof.

Also US 130, US 202, US 206, US 211, US 222, and US 522.