U.S. 49 joins the Mississippi Gulf Coast with the capital city of Jackson via Hattiesburg and Collins. The US Highway originates at U.S. 90 by ports facilities along Mississippi Sound in Gulfport. Comprising a heavily developed arterial, U.S. 49 connects Downtown Gulfport with I-10 and suburban areas to the north. The four lane corridor extends north to Saucier, Wiggins and U.S. 98 on the south side of Hattiesburg.
U.S. 98 bypasses Hattiesburg to the west along side I-59 while U.S. 49 follow an older arterial route west of Downtown to The University of Southern Mississippi. Northwest from Interstate 59, U.S. 49 serves regional and freight traffic to I-20 and I-55 at Richland and Pearl.
Through Jackson, U.S. 49 overlaps with I-20 west and I-220 north to circumvent the city. 205 miles from Gulfport, U.S. 49 travels to Yazoo City, where it splits into east and west branches. U.S. 49E loops through Greenwood while U.S. 49W connects with Indianola. The two converge at Tutwiler to the north, where U.S. 49 resumes northward 41 miles to Clarksdale, Lula and the Helena Bridge into Arkansas.
U.S. 49 Mississippi Highway Guides
Page Updated 03-21-2019.