Orientated from south to north in the Tar Heel State overall, U.S. 52 travels through central North Carolina. U.S. 52 enters the state north from Cheraw, South Carolina. North through Wadesboro, Albemarle and Salisbury, U.S. 52 constitutes a two to four lane highway. U.S. 52 combines with Interstate 85 northeast for 12.57 miles between Exit 76 south of Spencer and Exit 87 south of Lexington.

U.S. 52 joins Lexington and Winston-Salem alongside Interstate 285. Northwest from Winston-Salem, U.S. 52 is part of Future I-74 to Pilot Mountain and Mount Airy. The northernmost 10.18 miles in North Carolina travels at-grade around Mt. Airy to the Virginia state line south of Cana.

U.S. 52 North Carolina Guides

U.S. 52 South
A reassurance marker for U.S. 52 Bypass stands along the southbound on-ramp from NC 89 (Pine Street) at Mount Airy. U.S. 52 follows an older at-grade bypass through western and southern reaches of the city. 07/09/10
A freeway-style distance sign for Winston-Salem (36 miles) and Lexington (57 miles). U.S. 52 is a freeway from south of Bannertown to Interstate 85 at Lexington. 07/09/10
Snowhill Drive (SR 1371) stems east from U.S. 52 Bypass (Andy Griffith Parkway) and S Franklin Road to become Worth Street en route to U.S. 52 Business/NC 89 (Renfro Street) in Mt. Airy. 07/09/10
U.S. 52 Bypass advances south from Worth Street and to the north end of U.S. 601 at Rockford Street. 07/09/10
U.S. 601 leads south from Mt. Airy 22 miles to Yadkinville and 40 miles to Mocksville. Locally U.S. 601 was realigned through White Plains to meet Interstate 74 at a diamond interchange. 07/09/10
Rockford Street north of U.S. 52 Bypass was formerly a part of U.S. 601 to Main Street (old U.S. 52). U.S. 601 travels 319 miles overall south to U.S. 321 near Tarboro in the Lowcountry of South Carolina. 07/09/10
U.S. 52 scenes
Hickory Tree Road (SR 1508) branches northwest from Old U.S. 52 (SR 2923) at Midway to connect with I-285/U.S. 52-NC 8. 12/15/16
2 photos
2 photos
A parclo interchange joins Hickory Tree Road (SR 1508) with I-285/U.S. 52-NC 8. 12/15/16

Photo Credits:

07/09/10, 12/15/16 by AARoads

Connect with:
Interstate 74
Interstate 77
Interstate 85
U.S. 29
U.S. 70

Page Updated 08-10-2020.

Go to Top