Beginning in Downtown Cleveland, U.S. 422 in Ohio runs 74.96 miles southeast to Warren, Youngstown and the Pennsylvania state line. U.S. 422 overlaps with SR 43/87 east from Public Square along Ontario Street to I-90 (Innerbelt Freeway) at Orange Avenue. U.S. 422/SR 87 continue onto Woodland Avenue to E 55th Street and Kinsman Road in Cleveland's Central Neighborhood.
U.S. 422 shifts southeast onto Kinsman Road alongside SR 8 from SR 87 (Woodland Avenue) to Kinsman, Woodland Hills and Mt. Pleasant in Cleveland. The two routes part ways in the city of Shaker Heights where Chagrin Boulevard intersects Warrensville Center Road. U.S. 422 remains along Chagrin Boulevard east to Interstate 271.
Combining with I-271, U.S. 422 turns south to I-480N in Warrensville Heights and a freeway spur extending east to Solon and Auburn Corners in Geagua County. A short two lane section of U.S. 422 leads east to Welshfield. U.S. 422 expands to four lanes southeast from Parkman to the city of Warren.
U.S. 422 constitutes a commercial boulevard southeast from Warren into the cities of Niles and Girard. Within Youngstown, U.S. 422 bypasses Downtown and Youngstown State University along the Madison Avenue Freeway to U.S. 62 at Oak Street.
| U.S. 422 previously began along Ontario Street from Rockwell Avenue, which connected U.S. 6/20 west on Superior Street with the route south. Redevelopment of Cleveland Public Square included the removal of Ontario Street between Rockwell Avenue and S Roadway. 06/14/10 |
| The first confirming markers for U.S. 422 and SR 8/14 were formerly posted along Ontario Street south of U.S. 6/20 (Superior Avenue). The routes are not marker now. 09/30/10 |
| Prior to 1971, U.S. 21 overlapped with U.S. 422 south from Public Square along Ontario Street. 09/30/10 |
| Ontario Street south at S Roadway, which connected to the continuation of U.S. 20 along Euclid Avenue. S Roadway now represents the eastbound roadway for U.S. 6/20 around Public Square. 09/30/10 |
| A trailblazer for the Ohio Turnpike was posted at Ontario Street and S Roadway for the exchange joining SR 21 (old U.S. 21) with Interstate 80 in Richfield. 09/30/10 |
| U.S. 422/SR 8-14-87 (Ontario Street) proceed one block south from Public Square to Prospect Avenue. These reassurance makers were removed by 2007. 05/02/02 |
| U.S. 422/SR 8-14-87 (Ontario Street) shift eastward ahead of Huron Road and Rocket Mortgage Fieldhouse (home of the Cleveland Cavaliers). 08/10/06 |
| Reassurance markers for U.S. 422/SR 8-14 were replaced by 2007 with a separate assembly including SR 87. Those were removed by 2009. 08/10/06 |
| Rocket Mortgage FieldHouse and Progressive Field (home of the Cleveland Guardians) line Ontario Street between Huron Road and Carnegie Avenue. 08/10/06 |
| U.S. 422/SR 8-14 west conclude at S Roadway (U.S. 6/20 east) and Public Square in Downtown Cleveland. 09/30/10 |
| U.S. 322 west and U.S. 42 north also end at U.S. 6/20 and Public Square. U.S. 6/322 overlap east along Superior Avenue to E 13th Street. U.S. 42 combines with U.S. 6/20 (Superior Avenue) west across the Veterans Memorial Bridge to W 25th Street. 09/30/10 |
| Prior to the removal of Ontario Street from Public Square, the movement from U.S. 422 west to U.S. 6/20/42 west utilized Rockwell Avenue and W Roadway to connect with Superior Avenue. 06/14/10 |
| The former intersection of Ontario Street (U.S. 422) and Superior Avenue (U.S. 6/20/42/322). Superior Avenue was converted to a busway between W and E Roadways. 09/30/10 |
| Ontario Street was removed between S Roadway and Rockwell Avenue. U.S. 6/20 west were realigned from Superior Avenue onto Rockwell Avenue during the redevelopment of Public Square. 09/30/10 |
| Key Tower, the highest skyscraper in Cleveland, rises beyond Old Stone Church and the Society for Savings Building on the northeast side of Public Square. 08/10/06 |

scenes
SR 616 heads south from Hubbard in Trumbull County to U.S. 422 at Coitsville Township in Mahoning County.
11/13/04
Photo Credits: 11/13/04 by Carter Buchanan
Connect with:
Interstate 80
Interstate 90
Interstate 271
U.S. 6
U.S. 20
U.S. 62
U.S. 322
State Route 11
Page Updated 08-04-2021.