A 69.6 mile route through northeastern Massachusetts, Route 110 begins at Route 140 (Central Street) in West Boylston and ends at a split intersection with U.S. 1 and Route 1A in the Salisbury town center. The bulk of the highway comprises a local route parallel to Interstate 495 from Littleton to Amesbury. Westernmost sections of Route 110 connect Clinton with Wachusett Reservoir and Harvard.
| Interstate 495 merges onto I-95 northbound at Salisbury with no access to southbound. Route 110 provides that movement east from Macy Street to Elm Street. 07/29/07 |
| Route 110 transitions onto Elm Street east from ahead of I-95 to the Salisbury town center. 07/29/07 |
| Continuing east from the north side ramps of I-95, Route 110 (Elm Street) intersects Rabbit Road north and Merrill Street south by Cross Roads Plaza shopping center. 07/29/07 |
| Expanding to four lanes, Route 110 (Elm Street) leaves the intersection with Merrill Street and Rabbitt Road and enters a parclo interchange with Interstate 95.
Sign replacements made here by 2012 switched Kittery with Portland, Maine. 07/29/07 |
| Route 110 provides access from I-95 north to Interstate 495 south to Haverhill. Work associated with the 2013-17 Whittier Bridge replacement along I-95 included new overpasses for the freeway above Route 110. 07/29/07 |
| A loop ramp joins Interstate 95 southbound across the Whittier Bridge to Newburyport. 07/29/07 |
| Elm Street branches northwest from Route 110 to Downtown Amesbury as the state route transitions onto Macy Street west. 07/29/07 |
| Westbound Route 110 (Chelmsford Street) at Liberty Street west and Lincoln Street south in the city of Lowell. 07/29/07 |
| Plain Street branches east from Parker Street to intersect Route 110 (Chelmsford Street) at Powell Street. Plain Street east leads to ramps with the Lowell Connector, a three mile freeway connecting Downtown Lowell with I-495 and U.S. 3 in the town of Chelmsford.
Construction in 2008 reconfigured this intersection with new mast-arm traffic lights added. 07/29/07 |
| Plain Street leads west from ramps with the Lowell Connector to intersect Route 110 (Chelmsford Street) at Powell Street. 07/29/07 |
| Merrill Street curves northeast from Main Street and Newburyport to intersect Route 110 (Elm Street) across from Rabbitt Road in Salisbury. 07/29/07 |
| The easternmost extent of Route 110 joins I-95 and I-495 with the Salisbury town center and Salisbury Beach via Route 1A east. 07/29/07 |
Page Updated 09-20-2016.