Florida State Road 105 travels 15.06 miles east from Northside, Jacksonville to Fanning Island in Duval County. Following Zoo Parkway, SR 105 branches east from I-95 to adjacent U.S. 17 and Jacksonville Zoo and Gardens. The four lane arterial continues by industrial areas in Imeson Park to span the Broward River north of Drummond Point. Running along the north side of the St. Johns River, SR 105 crosses Dunn Creek east at Broward Point.
East of Interstate 295, SR 105 connects with Dave Rawls Boulevard south onto Blount Island. The four lane section ends as SR 105 (Heckscher Drive) straddles the north banks of the St. Johns River east to Browns Creek. The remainder of the state road runs between the river and Timucuan Ecological and Historic Preserve. The route concludes on Fanning Island, where SR A1A takes over along Heckscher Drive north from the Ft. George - Mayport Ferry.

East
SR 105 travels east from I-295, connecting the East Beltway with Blount Island, Ameila Island, and Fernandina Beach.
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Dave Rawls Boulevard crosses the St. Johns River to the Blount Island Marine Terminal.
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This reassurance marker stands ahead of Ramoth Drive on Little Marsh Island.
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The current high fixed-span replaced a bascule bridge built in 1952 over Sisters Creek by August 2016.1
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The current high fixed-span replaced a 1952-built bascule bridge over Sisters Creek by August 20161.
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The Mayport ferry service shuttles motorists across the St. Johns River to SR A1A south (Ocean Street) at Mayport.
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SR 105 east concludes as SR A1A joins Heckscher Drive to Amelia Island and Fernandina Beach.
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West
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August Drive stems south from SR 105 (Zoo Parkway) to the Jaxport Cruise Terminal.
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Zoo Parkway proceeds west across a bridge spanning the mouth of Dunn Creek.
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SR 105 turns north alongside the St. Johns River from Broward Point.
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SR 105 curves southwest from Eastport Road across the Broward River.
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Zoo Parkway lowers from the Broward River bridge by an industrial plant north of Drummond Point.
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Paralleling Drummond Creek, SR 105 reaches the entrance to Jacksonville Zoo & Gardens at Hayden Road.
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An access road links SR 105 (Zoo Parkway) with U.S. 17 (Main Street) south ahead of a folded diamond interchange between the two routes.
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A loop ramp joins U.S. 17 with SR 105 west one quarter mile ahead of Interstate 95.
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Page Updated Saturday April 18, 2020.