I-22/U.S. 78 West - Winfield to Hamilton


I-22/U.S. 78 advances through western reaches of the Brilliant town limits to the diamond interchange (Exit 26) with SR 44. SR 44 travels 10.00 miles between U.S. 43 in Guin and SR 129 in Brilliant.
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I-22/U.S. 78 meet SR 44 along the Guin city and Brilliant town lines at Exit 44, just ahead of Luxapallila Creek. SR 44 west leads into the town of Twin before continuing toward the Guin city center.
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Interstate 22 ascends westward from Luxapallila Creek to the SR 253 overpass in the city of Twin.
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Westbound I-22/U.S. 78 descend to Beaver Creek and a diamond interchange (Exit 22) with Marion County Route 45.
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Marion County Route 45 runs southwest to U.S. 43/278 outside Guin and northeast to SR 253 south of Pearces Mill.
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U.S. 43/278 serve Guin, eight miles to the south and the Marion County seat of Hamilton, centered five miles to the north.
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Marion County Route 35 stems 1.24 miles west from U.S. 43/278 in south Hamilton to I-22/U.S. 78 at Exit 14.
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Continuing southwest from Exit 14 and Hamilton, CR 35 travels to Henson Springs and SR 17 north of Sulligent.
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SR 17 branches 3.52 miles west from an overlap with U.S. 43/278 in Hamilton to the diamond interchange at Exit 11. The state route represents the hidden counterpart of U.S. 43 northward to Florence.
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SR 17 is part of a longer route serving connecting the Marion County seat of Hamilton with the towns of Sulligent and Detroit. The route travels through the Black Belt region of the state from Mobile to Tennessee by way of Florence.
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SR 74 runs 4.82 miles west from the north split of U.S. 43/278 in Hamilton to the diamond interchange at Exit 7.
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SR 74 intersects SR 19 to the immediate east of Exit 7. The state route runs north from west Hamilton to the town of Vina and SR 24 in the city of Red Bay.
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Following the original alignment of U.S. 78, Marion County Route 94 extends west from SR 74 and Exit 7 to Bexar and the Mississippi state line.
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CR 33 ties into CR 11, 0.75 miles north of Interstate 22. CR 11 leads north toward Shotsville.
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Photo Credits:
- ABRoads: 05/06/22
- Alex Nitzman: 06/16/22
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Page Updated Wednesday February 25, 2026.


