Interstate 290 East

The first confirming marker for Interstate 290 along the Youngmann Memorial Highway eastbound.
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Traveling east across the Town of Tonawanda, I-290 advances one mile from East Park Drive to Exit 1 for Elmwood Avenue south and Knoche Road.
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Parallel Knoche Road (CR 306) links Exit 1 with NY 265 (Military Road) 0.21 miles to the west and NY 384 (Delaware Avenue) 0.25 miles to the east.
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Elmwood Avenue stems 0.91 miles south from the ramps at Exit 1 through Mount Olivet Cemetery to NY 324 (Sheridan Drive) and 2.45 miles to Kenmore Avenue along the Kenmore and Buffalo city line.
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NY 384 (Delaware Avenue) connects with Interstate 290 directly at a cloverleaf interchange preceding this eastbound confirming marker.
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NY 425 commences a 22.14 mile long route north to NY 18 at the village of Wilson along Lake Ontario from Interstate 290 at Exit 2.
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Colvin Boulevard extends south from the parclo interchange (Exit 2) with NY 425 into the Town of Tonawanda.
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A three quarter cloverleaf interchange links Interstate 290 with U.S. 62 (Niagara Falls Boulevard) at Exit 3, a half mile from I-990 (Lockport Expressway) north.
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U.S. 62 follows Niagara Falls Boulevard north from NY 324 by the Brighton community in Tonawanda to the northeast side of the North Tonawanda.
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U.S. 62 heads south to Eggertsville and Buffalo. Nationally the route travels to El Paso, Texas.
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U.S. 62 arcs northwest to Niagara Falls. Interstate 990 branches northeast to the University at Buffalo (UB) and Getzville.
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Interstate 990 (Lockport Expressway) spurs 6.53 miles northeast to NY 263 (Millersport Highway).
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The Lockport Expressway was originally proposed to continue north to the city of Lockport. Interstate 990 was completed east to NY 263 in 1990.
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Interstate 290 converges with NY 263 (Millersport Highway) at a cloverleaf interchange (Exit 5) one half mile southeast from the exchange with I-990.
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North from Exit 5 B, NY 263 (Millersport Highway) encircles the UB campus to the south and east.
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The parclo interchange at Exit 6 joins Interstate 290 with NY 240 (Harlem Road) just south of NY 324 (Sheridan Drive) near Snyder in the town of Amherst.
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NY 5 (Main Street) heads east from Snider to a directional cloverleaf interchange (Exit 7) with Interstate 290.
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Paralleling I-90 (NYS Thruway) to the north, NY 5 (Main Street) continues east from Exit 7 B into the village of Williamsville.
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Interstate 290 ties into I-90 at a directional T interchange between the tolled section of the NYS Thruway east to Rochester and the free section south by Buffalo.
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Interstate 90 travels across Upstate New York west from Buffalo to Dunkirk and the Pennsylvania line in the town of Ripley and east to Syracuse, Albany and Massachusetts from the town of Canaan.
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