U.S. 78 West

U.S. 78 (University Boulevard) branches west from U.S. 52 by North Charleston Wannamaker County Park.
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U.S. 78 west at Von Ohsen Road (Road 169) south and Royle Road (Road 535) north.
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U.S. 78 (E 5th Street N) west enters the town of Summerville ahead of S.C. 165 (Berlin G. Myers Parkway).
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S.C. 165 north provides a cutoff from U.S. 78 west to U.S. 17 ALT (N Main Street) to Moncks Corner.
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U.S. 17 ALT runs across Summerville along Main Street west to Walterboro and northeast to Moncks Corner.
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U.S. 78 (W 5th Street N) at Bryan Street (Road 187) south and Iris Street north in Summerville.
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The flashers at N Maple Street (Road 131) and U.S. 78 (W 5th Street N) were upgraded to traffic lights by 2011.
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Shifting west to parallel a Norfolk Southern Railroad line, U.S. 78 (W 5th Street N) converges with W Richardson Avenue (Road 65) at Auburn Hill Road.
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Jedburg Road (Road 58) south and Mallard Road (Road 58) north come together at a signalized intersection with U.S. 78 (W 5th Street N) in Jedburg.
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U.S. 78 crosses Green Bay Branch northward from Jedburg.
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Running northwest from Cypress Swamp, U.S. 78 meets S.C. 173 (School Street) west at Myers Mayo Road (Road 182).
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A 1.57 mile long route, S.C. 173 joins U.S. 78 with S.C. 27 (Church Street) in the town of Ridgeville.
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U.S. 78 west at Stable Lane (Road 69) and Quinton Drive.
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S.C. 27 (Church Street) travels 7.84 miles southwest from U.S. 78 to Ridgeville and S.C. 61.
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Widening of U.S. 78, from 0.35 miles southeast of S.C. 35 to 0.8 miles west of U.S. 178, ran from 2019 to an anticipated completion of August 12, 2021.
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S.C. 27 combines with U.S. 78 west for 0.49 miles to Ridgeville Road.
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The construction of Ridgeville Commerce Park along the south side of U.S. 78 in 2013/14 included realigning S.C. 27 westward to a signalized intersection with the new entrance.
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U.S. 78 continues north from S.C. 27 as both a hurricane evacuation route and South Carolina Heritage Corridor Discovery Route.
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U.S. 78 crosses Four Hole Swamp over a pair of bridges. The first span was replaced by 2018.
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U.S. 178 previously commenced north from U.S. 78 at a wye intersection beyond the Minus Bridge over Four Hole Swamp.
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Road work expanding U.S. 78 west included realigning U.S. 178 to meet the route at a new intersection perpendicular.
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U.S. 178 parallels Interstate 26 to the west through Harleyville, Bowman and Orangeburg.
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Sandhill Road (Road 248) connects U.S. 78 at Dorchester with U.S. 178 (E Main Street) north to Harleyville in 1.67 miles.
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U.S. 78 west enters the town of St. George along Jim Bilton Boulevard.
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U.S. 78 (Memorial Boulevard) meets U.S. 15 (Parler Avenue) at the St. George business district.
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Shields for U.S. 15, U.S. 78 and I-95 at Memorial Boulevard and Parler Avenue were removed when span wire traffic lights were changed to mast arms in 2013.
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The St. George town limits extend along U.S. 78 (Jim Bilton Boulevard) west to the folded diamond interchange (Exit 77) with Interstate 95.
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U.S. 78 (Johnston Avenue) west at Rigby Street (Road 16) in Reevesville.
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U.S. 78 dog legs south alongside U.S. 21 (Freedom Road) 0.20 miles from Dorange Road to Edward Street in Branchville.
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U.S. 21 travels north from Branchville to Orangeburg and Columbia.
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