
South
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U.S. 221 turns south onto Church Street from Whitney Road just beyond the exchange with I-585/U.S. 176/S.C. 9 (N Pine Street).
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U.S. 221 (Church Street) intersects Catawba Street at Spartanburg Medical Center hospital.
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Curving southeast toward Downtown Spartanburg, U.S. 221 (Church Street) converges with S.C. 56 (Asheville Highway) eastbound.
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S.C. 56 (Asheville Highway) runs northwest to Lone Oak, Southern Shops and U.S. 176 (N Pine Street) beyond Interstate 85.
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South

East
U.S. 221/S.C. 56 overlap 1.29 miles south along Church Street to E Henry Street.
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Evins Street stems east from Church Street onto the campus of Wofford College.
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Daniel Morgan Avenue was formerly part of S.C. 296. S.C. 296 branches west from U.S. 29 (W Main Street) along John B. White, Sr. Boulevard to I-26 at Exit 22.
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Page Updated Wednesday March 09, 2022.