U.S. 378 West - McCormick to Georgia

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S.C. 67 (Callison Highway) stems 14.30 miles north from U.S. 378 to U.S. 25/178 near Greenwood.
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Walker Road (Road 35) extends 8.83 miles southeast from U.S. 378/S.C. 67 to S.C. 283 (Plum Branch Road).
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15.60 miles remain along U.S. 378 west in South Carolina across McCormick County.
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U.S. 378 (E Gold Street) and U.S. 221 (Greenwood Highway) combine just north of the McCormick street grid.
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U.S. 221/378 (Gold Street) south at Main Street in Downtown McCormick.
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U.S. 221 splits with U.S. 378 west to join S.C. 28 south at Mine Street.
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A new bridge for U.S. 378 across the Savannah River was completed in 2016.
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The mid point of the Savannah River marks the Lincoln County, Georgia line along U.S. 378 west.
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