SR 121 combines with U.S. 27/41 (Main Street) 0.44 miles north from U.S. 27 ALT (Nobile Avenue) to NE 6th Boulevard in Williston.
12/07/07
SR 121 north separates with U.S. 27/41 (N Main Street) beyond N 4th Avenue.
12/07/07
12/07/07
A lane drop occurs along U.S. 27/41 (N Main Street) at the split with SR 121 (NE 6th Boulevard). SR 121 continues 16 miles north to Interstate 75 at Gainesville.
12/07/07
MSR 121 extends north from Gainesville to Lake Butler, Macclenny and Folkston, Georgia.
12/07/07

North
12/07/07
12/07/07
Remaining on U.S. 41 north, Lake City is 59 miles from Williston.
12/07/07
CR 318A lines NE 50th Street 1.25 miles east from U.S. 27/41 to CR 331A (NE 13th Street) across northeast Williston.
12/07/07
12/07/07
12/07/07
CR 343 (NE 60th Street) bee lines 7.17 miles west from U.S. 27/41 to U.S. 27 ALT near Spring HIll.
12/07/07
Continuing northwest, U.S. 27/41 next reach the settlement of Raleigh.
12/07/07
CR 335 (NE 75th Street) crosses paths with U.S. 27/41 at Raleigh.
12/07/07
CR 335 previously began from U.S. 27 north along the Levy / Marion County line.
12/07/07
Confirming markers posted north of SR 26 (Newberry Road) along NW 250th Street in Newberry.
04/17/19
04/17/19
U.S. 27/41 narrow from a four lane arterial at NW 8th Place in Newberry.
04/17/19
U.S. 27/41 north after NW 32nd Avenue.
04/17/19
NW 78th Avenue doubles as CR 232 west from CR 241 (NW 143rd Street) and the Alachua city line to U.S. 27/41 at northern reaches of Newberry.
04/17/19
West from Newberry, CR 232 extends 12.27 miles to U.S. 129 near Bell in Gilchrist County.
04/17/19
04/17/19
Reassurance markers posted north of NW 174th Avenue in High Springs.
01/16/16
CR 340 is a rural highway traveling 23.30 miles west from U.S. 27/41 in High Springs to SR 349 in northeastern Dixie County.
01/16/16
Poe Springs, Blue Springs and Ginnie Springs lie along the Santa Fe River to the north of CR 340.
01/16/16
01/16/16
SR 20 branches a half mile west from U.S. 441 along NW 186th Avenue to U.S. 27/41 (Main Street) in Downtown High Springs. SR 20 is unsigned southeast along U.S. 441 through Alachua and northwest alongside U.S. 27 to Fort White and Tallahassee.
01/16/16
U.S. 27 turns west from U.S. 41 (Main Street) along NW 1st Avenue while U.S. 41 remains on Main Street north 0.23 miles to U.S. 441. U.S. 41/441 overlap north to Lake City while U.S. 27 connects Branford and Mayo with U.S. 19/98 at Perry.
01/16/16
Page Updated 07-26-2023.