U.S. 221 North

The first confirming marker for U.S. 221 stands at Park Street adjacent to U.S. 19/98/27 ALT.
10/02/21

Madison Street intersects U.S. 221 (Jefferson Street) adjacent to big box retail.
10/02/21

Church Street is unsigned CR 2128, which leads west to U.S. 19/98/27 ALT (Burn Butler Parkway) and east to Old Dixie Highway (CR 2131).
10/02/21

Old Dixie Highway (CR 2130) converges with U.S. 221 three blocks ahead of U.S. 27 (Hampton Springs Avenue).
07/27/22

The previous truck route for U.S. 221 circumvented Jefferson Street and Downtown Perry via U.S. 27 west to U.S. 19/27 north. It became part of the mainline route in 2019, and signs were finally changed in 2021.
07/27/22

U.S. 221 overlaps with U.S. 27 (Hampton Springs Avenue) 0.42 miles west to U.S. 19 (Byron Butler Parkway). U.S. 27 leads east from Perry to Mayo and Branford.
07/27/22

Shields for U.S. 221 and U.S. 27 stand along Hampton Springs Avenue between Jefferson Street and Quincy Street.
10/02/21

10/02/21

10/02/21

U.S. 19/98/27 ALT loop west from U.S. 221 along Jefferson Street to meet the route again with U.S. 27 (Hampton Springs Avenue) along Byron Butler Parkway.
10/02/21

U.S. 27 ALT ends where U.S. 27/221 combines with U.S. 19 (Byron Butler Boulevard) north. The bannered route runs south with U.S. 19/98 to Chiefland and east to U.S. 27/41 at Williston.
10/02/21

The relocation of U.S. 221 made in 2021 replaced what was the truck route.
10/02/21

U.S. 98 separates with U.S. 19 west toward Tallahassee and the Emerald Coast. U.S. 19 continues northwest with U.S. 27 to Capps.
10/02/21

U.S. 19/27/221 overlap 2.79 miles northwest from Hampton Springs Avenue to Wright Road outside Perry.
06/16/22

06/16/22

06/16/22

06/16/22

06/16/22

06/16/22

There are no services for the next 15 miles along U.S. 19/27 beyond Ash Street and Perry.
06/16/22

U.S. 221 separates with U.S. 19/27 for Wright Road where CR 359A east ties in from Slaughter Road.
06/16/22

06/16/22

06/16/22

U.S. 221 runs 1.35 miles east along Wright Road (SR 359A) back to its original alignment north of Perry.
10/02/21

Old U.S. 221 south to Jefferson Street and the Perry city line is unsigned CR 55.
10/02/21

Confirming marker posted north of Wright Road (SR 359A).
10/02/21

U.S. 221 bee lines northward from Perry to the settlement of Lake Bird.
06/02/06

Taylor County Road 14 travels 7.24 miles east from U.S. 19/27 at Eridu to U.S. 221.
06/02/06

Crossing the Econfina River, northbound U.S. 221 reaches the rural community of Shady Grove.
06/02/06

CR 14 (Alton Wentworth Road) continues northeast from Shady Grove to Interstate 10, where it upgrades to SR 14 to the city of Madison.
06/02/06

06/02/06

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06/02/06

06/02/06

The eastern branch of CR 158 (Sundown Creek Road) runs 10.08 miles from U.S. 221 to CR 14.
06/02/06

06/02/06

10/05/16

U.S. 221 proceeds north from CR 158 (Sundown Creek Road) into a diamond interchange with Interstate 10.
10/05/16

Interstate 10 travels west to Tallahassee and east to Lake City and Jacksonville.
10/05/16

10/05/16

10/05/16

01/16/16

Approaching CR 150 west on Overstreet Avenue.
01/16/16

CR 150 meanders 14.91 miles southwest from U.S. 221 at Greenville to U.S. 19/27.
01/16/16

U.S. 221 enters the town of Greenville just beyond CR 150 (Overstreet Avenue).
01/16/16

U.S. 221 meets U.S. 90 on the east side of Downtown Greenville.
01/16/16

U.S. 221 combines with U.S. 90 west for 0.31 miles. U.S. 90 ventures east from Greenville to Madison.
01/16/16

U.S. 90 west and U.S. 221 north overlap along the north side of Downtown Greenville and Haffye Hays Park.
01/16/16

U.S. 90 reduces to a two lane highway at the split with U.S. 221 north.
01/16/16

U.S. 90/221 cross a Georgia & Florida Company Railroad line at Leggett Avenue just ahead of their separation.
01/16/16

U.S. 90 continues west from U.S. 221 and Greenville to Monticello. U.S. 221 resumes a northward heading to Ashville.
01/16/16

Leaving Greenville, U.S. 221 passes through a residential area ahead of CR 140.
01/16/16

01/16/16

CR 140 loops west of U.S. 221 and then back east across the highway to CR 150 along Lovett Road.
01/16/16

01/16/16

01/16/16

09/01/08

09/01/08

09/01/08

Advancing north from Ashville, U.S. 221 travels between agricultural fields and timber land toward the Georgia state line.
04/19/09

U.S. 221 (Quitman Highway) enters Brooks County, Georgia. SR 76 accompanies the route along Greenville Highway north to Quitman.
04/19/09