


U.S. 221 enters Jefferson County, Florida from Brooks County, Georgia. Unmarked SR 55 begins here.
06/04/17

CR 146 stems 14.10 miles west from U.S. 221 along Ashville Highway to the Jefferson County seat of Monticello.
06/04/17

CR 140 constitutes a 4.76 mile route east to CR 150 (Lovett Road) and south along a loop to the west of U.S. 221.
04/19/09




Departing Greenville, U.S. 221 progresses 13 miles south to Shady Grove and 26 miles to Perry.
08/07/06

Reassurance marker posted after the unmarked intersection with CR 361 (Shiloh Church Road west / Roberts Aman Road east).
12/11/07

A second branch of CR 361 ties into U.S. 221 ahead of this shield assembly from Pisgah Road to the west.
12/11/07

CR 359A stems 1.35 miles west along Wright Road from U.S. 221 to U.S. 19/27 at Slaughter Road. CR 359A west to U.S. 19/27 south was part of the U.S. 221 truck route previously.
12/11/07

CR 359A was upgraded to SR 359A as part of the realignment of U.S. 221 west to avoid Downtown Perry.
10/02/21

U.S. 221 combines with U.S. 19/27 southeast 2.79 miles to U.S. 98 and Hampton Springs Avenue in Perry.
10/02/21




Reassurance markers for U.S. 19/27/221 posted south of the signalized intersection with Ash Street (CR 361).
07/27/22

CR 356 heads west from Perry 1.94 miles to CR 359 (Poppel Road) north and CR 361B (Woods Creek Road) west.
05/02/20

U.S. 98 ties into U.S. 19/27/221 (Byron Butler Parkway) along Hampton Springs Avenue east from Hampton Springs outside Perry.
05/02/20

U.S. 221 dog legs east along U.S. 27 (Hampton Springs Avenue) 0.42 miles to rejoin its original alignment along Jefferson Street.
05/02/20

The truck route for U.S. 221 follows U.S. 19/98 to the south end of U.S. 221 (Jefferson Street) at CR 361A.
05/02/20



U.S. 221 parts ways with U.S. 27 (Hampton Springs) south onto Jefferson Street. Jefferson Street north follows the old route across Spring Creek and a Georgia & Florida Company Railroad line into Downtown Perry.
11/23/08

U.S. 27 continues 27.8 miles east from U.S. 221 (Jefferson Street) to SR 51 in the Lafayette County seat of Mayo.
07/27/22


Jefferson Street expands to a five lane commercial boulevard from U.S. 27 southward. Old Dixie Highway (CR 2131) diverges from U.S. 221 in three blocks.
04/19/09

The final confirming marker for U.S. 221 southbound stands beyond the split with Old Dixie Highway.
04/19/09

Church Street (CR 2128) intersects U.S. 221 west from Old Dixie Highway (CR 2131) to U.S. 19/98/27 ALT (Byron Butler Parkway).
12/31/06

U.S. 19/98/27 Alternate combine southward from Hampton Springs Avenue (U.S. 27/221) to Cross City and Chiefland.
05/02/20
Photo Credits:
- 08/07/06 by AARoads.
- 12/31/06 by AARoads.
- 07/19/07 by AARoads.
- 12/11/07 by AARoads.
- 09/01/08 by AARoads.
- 11/23/08 by AARoads.
- 04/19/09 by AARoads.
- 04/10/10 by AARoads.
- 01/16/16 by AARoads.
- 06/04/17 by AARoads.
- 05/02/20 by AARoads.
- 10/02/21 by AARoads.
- 07/27/22 by AARoads and JP Nasiatka.
Connect with:
Interstate 10
U.S. 19
U.S. 27
U.S. 90
U.S. 98
State Road 14 / County Road 14
County Road 146
County Road 158 / County Road 1540
County Road 361
Page Updated 08-02-2023.