U.S. 301 South - Bamberg to Georgia

Angling southwest from U.S. 601 and Bamberg, U.S. 301 (Main Highway) expands to a four lane, divided highway.
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U.S. 301 turns southward ahead of Lemon Creek.
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South at Springtown, U.S. 301 (Main Highway) crosses the Little Salkehatchie River.
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Ehrhardt Road (Road 22) runs 4.44 miles west to U.S. 321 (Carolina Highway) in the town of Govan.
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S.C. 64 (Low Country Highway) crosses paths with U.S. 301 (Main Highway) 2.33 miles southeast from U.S. 321 (Carolina Highway) in the town of Olar.
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S.C. 64 travels west from U.S. 301 to the Barnwell County seat of Barnwell and to Snelling by the Savannah River Site.
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S.C. 64 was once considered as the corridor for the proposed eastward extension of U.S. 278 from Augusta, Georgia.
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S.C. 64 east combines with U.S. 301 (Main Highway) south for 0.36 miles.
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S.C. 64 resumes along Low Country Highway southeast to Ehrhardt, Lodge, Walterboro and U.S. 17 in the LowCountry.
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U.S. 321 (Carolina Highway) converges with U.S. 301 (Main Highway) south from Govan and Olar.
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U.S. 301 (Main Highway) south combines with U.S. 321 (Carolina Highway) south at a wye intersection at Bufords Bridge.
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U.S. 301/321 overlap from Bufords Bridge southwest to Ulmer before splitting on respective routes to Allendale and Fairfax.
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U.S. 321 was previously acknowledged on the succeeding shield assembly at Bufords Bridge.
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U.S. 301/321 (Bufords Bridge Highway) span the Salkehatchie River southwest into Allendale County.
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U.S. 301/321 transition into a five lane boulevard at the town of Ulmer.
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U.S. 301/321 part ways at a wye intersection ahead of Ulmer Road (Road 48).
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U.S. 301 shifts onto Burtons Ferry Highway southwest to Allendale and the Georiga line ahead of Sylvania. U.S. 321 remains on Bufords Bridge Highway south en route to Sycamore and U.S. 17 at Hardeeville.
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S.C. 300 (Wells Branch Road) stems north from U.S. 301 (Burtons Ferry Highway) at Ulmer.
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S.C. 300 runs 11.46 miles north to U.S. 278 outside Barnwell.
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S.C. 641 (Confederate Highway) ties into U.S. 301 west from the town of Sycamore.
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No other shield or guide signs is posted at the west end of S.C. 641 on U.S. 301 southbound. S.C. 641 travels 21.3 miles east to S.C. 64, south of Lodge.
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Advancing south to U.S. 278 (Barnwell Highway) along U.S. 301 (Main Street). A road diet reduced the boulevard from four lanes to two with a center turn lane.
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U.S. 278 travels north from Allendale to Kline and Barnwell.
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Beyond Barnwell, U.S. 278 circumvents the Savannah River Site northwest to North Augusta and Augusta, Georgia.
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U.S. 278/301 (Main Street) south at Bay Street in Downtown Allendale.
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U.S. 278 separates from U.S. 301 (Main Street) south at Allendale-Fairfax Highway and S.C. 125 (Augusta Highway) north.
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U.S. 278 continues southeast to Hampton while S.C. 125 runs northwest to the Savannah River Site and U.S. 278 at Beech Island.
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Reassurance marker posted west of Bluff Road (Road 22).
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S.C. 3 (River Road) loops west of U.S. 278 from south of Barnwell to northern Jasper County.
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S.C. 3 (River Road) arcs southeast 20.9 miles to U.S. 321 in the town of Estill.
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Passing by the former South Carolina Welcome Center along the northbound roadway for U.S. 301.
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The four lane section of U.S. 301 concludes south ahead of Chert Quarry Road (Road 102).
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The original roadway for U.S. 301 along Burtons Ferry Highway was repurposed as the Lower Savannah River Alliance Greenway.
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Chert Quarry Road (Road 102) leads 9.19 miles north to the Archroma chemical plant and S.C. 125 (Augusta Highway) at Martin.
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U.S. 301 traverses wetland areas west from Brier Creek to the Savannah River.
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The abandoned roadway for the old Burton's Ferry Bridge appears along the south side of U.S. 301, just east of the Savannah River.
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Connecting with a swing bridge across the Savannah River, the old viaduct for U.S. 301 remains intact.
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Replacing the adjacent span, the Burton's Ferry Bridge along U.S. 301 was built in 1965.
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