I-81 through I-84 and Signed Branch Routes

Interstate South/West End North/East End
81 near Dandridge, TN Canadian Border – Alexandria Bay, NY
381 VA Bristol, VA Bristol
481 NY DeWitt North Syracuse
581 VA Roanoke north of Roanoke
781 NY Watertown Fort Drum
82 Ellensburg, WA Hermiston, OR
182 WA west of Richland Pasco
83 Baltimore, MD Colonial Park, PA
283 PA Highspire Oakleigh
84 (west) Portland, OR Echo, UT
84 (east) Dunmore, PA Sturbridge, MA
184 ID Boise Downtown Boise
384 CT East Hartford Bolton Notch
684 NY/CT Rye/White Plains Brewster
I-81 north at US 211 - New Market, VA
Interstate 81 north at Exit 264 for U.S. 211 at new Market, Virginia. 09/23/14

U.S. 211 concludes a 59-mile route from Warrenton, Virginia at Interstate 81. Other U.S. highways ending at an Interstate include U.S. 151 at I-80 near Williamsburg, Iowa, U.S. 641 at I-40 near Holladay, Tennessee and U.S. 189 at I-15 in Provo, Utah.

I-83 north at Dauphin County, PA
Spanning the Susquehanna River along Interstate 83 north at Harrisburg, Pennsylvania. 06/21/12

I-83 was designated in 1960 to replace the route of U.S. 111 between Harrisburg and Baltimore, Maryland. U.S. 111 was decommissioned in 1963.