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IL 146 crosses Interstate 57 at a diamond interchange (Exit 30) in one mile.
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The Johnson County seat of Vienna lies east along IL 146 at U.S. 45 and Interstate 24.
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The town of Anna and the Union County seat of Jonesboro lie west along IL 146.
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U.S. 51 converges with Interstate 57 at a wye interchange, 7.2 miles southeast from IL 146 in the town of Anna.
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U.S. 51 overlaps with I-57 south from just ahead of Exit 24 to Dongola Road to Exit 1 and Cairo.
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U.S. 51 parts ways with I-57 south at Exit 1 where IL 3 ties in from unincorporated Klondike to the west.
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U.S. 51 branches southeast from I-57 through unincorporated Future City and the city of Cairo. IL 3 parallels the Mississippi River northwest to Thebes and Chester.
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U.S. 51 combines with U.S. 60/62 east in 5.1 miles across the Ohio River into Kentucky. U.S. 60/62 span the Mississippi River south from U.S. 51 in Cairo to Missouri.
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22.7 miles of Interstate 57 south remain to the cloverleaf interchange joining I-55 and U.S. 60 at Sikeston, Missouri.
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Interstate 57 spans the Mississippi River just north of the confluence with the Ohio River.
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The span across the Mississippi River along Interstate 57 is a through arch bridge.
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Angling southwest, Interstate 57 enters the Show Me State midway across the Mississippi River.
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Page Updated 12-30-2019.