Highway 341

Measuring 93.87 miles in length, S.C. 341 travels northwest from S.C. 41 (Georgetown Highway) at Johnsonville to U.S. 521-601 Business (Hampton Street) in Kershaw. The highway parallels Lake Swamp west to Lake City across southern Florence County. Through Lake City, S.C. 341 combines with U.S. 378 Business for 2.94 miles along Irby Street and W Main Street.

Following a 0.26 mile long overlap with U.S. 378 outside Lake City, S.C. 341 branches northwest to U.S. 301 at Olanta in southwest Florence County. S.C. 341 travels across eastern Sumter County where it meets Interstate 95. Northwest into Lee County, S.C. 341 continues to U.S. 76 at Lynchburg en route to I-20 and Bishopville.

S.C. 341 joins U.S. 15/S.C. 34 (Main Highway) north from Downtown Bishopville 1.39 miles to Bethune Highway. Mirroring the course of the Lynches River, the state highway advances north into Kershaw County ahead of U.S. 1 at Bethune. Crossing the Little Lynches River near Abney Crossroads, S.C. 341 leads northwest to the Lancaster County city of Kershaw.

North

S.C. 341 (Bethune Highway) crosses Bells Branch north of Benjie Lane and 2.9 miles from U.S. 15.
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Reassurance marker posted north of Stokes Bridge W Road (Road 26).
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S.C. 341 enters Kershaw County northbound ahead of Tillersville.
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S.C. 341 (Bethune Road) meets Old Stagecoach Road (Road 15) at Tillersville.
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Lowering 60 feet in elevation from Stagecoach Road, S.C. 341 (Bethune Road) north crosses the Little Lynches River.
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S.C. 341 enters the town of Bethune at Mary Dell Lane along Main Street.
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Main Street intersects U.S. 1 (King Street) in Downtown Bethune.
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U.S. 1 leads northeast to McBee and Cheraw and southwest to Camden and Columbia.
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Stop signs at U.S. 1 (King Street) and S.C. 341 (Main Street) were replaced with traffic lights by 2013.
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S.C. 341 continues northwest from Bethune to Kershaw. U.S. 521 heads north from there toward Charlotte, North Carolina.
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South

S.C. 341 (Lynches River Road) south enters a rural diamond interchange (Exit 146) with Interstate 95, 1.08 miles east of the Lee County line.
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Connect with:

Interstate 20

Interstate 95

U.S. 1

U.S. 15

U.S. 76

U.S. 301

U.S. 378

Highway 34

Highway 53

Highway 403

Page Updated Friday December 02, 2022.