U.S. 76

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U.S. 76 travels 296.65 miles across the width of South Carolina from the Chattooga River and Georgia state line in Oconee County to the North Carolina line at Gapway Swamp in northern Horry County. U.S. 76 traverses areas of Sumter National Forest southeast to Westminster in westernmost reaches of the state. The route overlaps with U.S. 123 east to Seneca and Clemson before turning south to Pendleton and Anderson.

U.S. 76 combines with U.S. 178 south into the Anderson County seat. The two also overlap with U.S. 29 Business/S.C. 81 for 0.73 miles along Murray Avenue through Downtown and with U.S. 29 for 0.85 miles east from Toxaway. U.S. 76/178 continue east to Belton and Honea Path before parting ways for Laurens and Greenwood respectively.

Through Laurens, U.S. 76 follows an arterial bypass to the north of Downtown while U.S. 78 Business lines Main Street to the city center along a 3.88 mile long course. U.S. 76 advances east to Clinton where it turns south along the I-26 corridor to Joanna, Newberry and Chapin.

Heading into the Columbia metropolitan area and Richland County, U.S. 76/176 overlap for 3.00 miles to Interstate 26. U.S. 76 shifts onto I-26 from Irmo south to St. Andrews, and I-126 east into the capital city. U.S. 76 runs concurrent with portions of U.S. 21/176/321 along Elmwood Aenue and U.S. 1/378 on Gervais Street leading away from Downtown.

Turning southeast from U.S. 1 at Waverly in Columbia, U.S. 76/378 remain paired to the freeway bypass to the north of Sumter. A second business route for U.S. 76 loops 5.91 miles south to Downtown Sumter, partly alongside U.S. 521. East from the city, U.S. 378 continues to Turbeville and Conway while U.S. 76 turns northeast to Timmonsville and Florence.

U.S. 76 runs across Florence, meeting U.S. 52 at Downtown and combining with U.S. 301 for 8.83 miles from S.C. 327 and the eastern bypass to western Marion County. U.S. 76 advances to Marion, Mullins and Nichols en route to Fair Bluff, North Carolina.

U.S. 76 South Carolina Guides

U.S. 76 West

U.S. 76 (Princeton Highway) crosses Little Creek southwest of Horseshoe Road (Road 254).
04/14/12

Reassurance marker posted west of Shady Grove Road (Road 81) north and Broadmouth Church Road (Road 81) south.
04/14/12

U.S. 76 (Princeton Highway) leads southwest into the town of Honea Path.
04/14/12

S.C. 252 travels northwest from Greenwood to E Greer Street in Honea Path.
04/14/12
U.S. 76 S.C. Highway 252 West

S.C. 252 and U.S. 76 overlap 0.56 miles west along Greer Street into the Honea Path business district.
04/14/12

U.S. 178 (Church Street) ties into U.S. 76/S.C. 252 (Greer Street) north from Donalds.
04/14/12

U.S. 178 travels southeast from Honea Path to Greenwood. S.C. 184 meets U.S. 178 at Donalds, east of the town of Due West.
04/14/12
U.S. 76 U.S. 178 West

U.S. 78/178 overlap northwest from Honea Path to Belton and then southwest to the city of Anderson.
04/14/12

U.S. 78/178 (Belton Honea Path Highway) north of G.W. Stevens Road at High Point.
04/14/12

U.S. 78/178 enter the city of Belton along S Main Street.
04/14/12


04/14/12

U.S. 78/S.C. 28 (Clemson Boulevard) cross Lake Hartwell ahead of the cloverleaf interchange (Exit 19) with Interstate 85.
07/23/04

U.S. 76/S.C. 28 continue northwest from I-85 near Anderson to Sandy Springs, Pendleton and Clemson.
07/23/04



    Connect with:
    Interstate 20
    Interstate 26
    Interstate 77
    Interstate 85
    Interstate 95
    Interstate 126
    U.S. 1
    U.S. 21
    U.S. 25
    U.S. 123
    U.S. 176
    U.S. 178
    U.S. 321
    U.S. 378

    Page Updated 12-07-2022.

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