U.S. 1 South - Columbia to Lexington

U.S. 1/378 (Gervais Street) west at Marion Street in Downtown Columbia.
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Gervais Street at Sumter Street.
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Gervais Street intersects Main Street north at the South Carolina State House.
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Assembly Street is part of S.C. 48 north to U.S. 21/76/176/321 (Elmwood Avenue) by the Elmwood neighborhood and south to the University of South Carolina (USC) campus.
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U.S. 1/378 (Gervais Street) next intersect Park Street one block west of S.C. 48 (Assembly Street).
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U.S. 1/378 (Gervais Street) span two sets of CSX Railroad tracks west of Wayne Street.
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A trailblazer for I-26 stands along Gervais Street at Pulaski Street.
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U.S. 21/176/321 turn south from U.S. 76 (Elmwood Avenue) at Interstate 126 along Huger Street.
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U.S. 21/176/321 continue six blocks south from U.S. 1/378 (Gervais Street) to Blossom Street west near USC and Founders Park.
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U.S. 1/378 proceed west from Williams Street onto the Gervais Street Bridge spanning the Congaree River.
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U.S. 1/378 partition just into West Columbia for Meeting Street and Sunset Boulevard respectively. Both routes meet Interstate 26.
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U.S. 378 follows Sunset Boulevard to the north while U.S. 1 continues along Meeting Street to Augusta Road. The two routes reconvene in Lexington.
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Unmarked from U.S. 1 (Meeting Street), State Street south from adjacent U.S. 378 (Sunset Boulevard) is part of S.C. 2. 3.94 miles long, S.C. 2 runs south to Frink Street in Cayce and west to U.S. 21/176/321.
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9th Street north 0.45 miles from U.S. 1 (Meeting Street) is S.C. 12 Connector. The state highway links Meeting Street with the parallel expressway along S.C. 12 (Jarvis Klapman Boulevard) and U.S. 378 (Sunset Boulevard).
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U.S. 1 separates with Meeting Street for Augusta Road adjacent to Charleston Highway (U.S. 21 Connector) south. Charleston Highway angles southwest 0.85 miles to U.S. 21/176/321 at Knox Abbott Drive.
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12th Street is S.C. 35 north to U.S. 378 (Sunset Boulevard) at Seminole Drive and south to Cayce and the 12th Street Extension to Interstate 77.
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U.S. 1 (Augusta Road) advances west through a commercialized stretch between S.C. 12 (Jarvis Klapman Boulevard) and a cloverleaf interchange with Interstate 26.
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Confirming marker posted west of the parclo A2 interchange (Exit 58) with Interstate 20.
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U.S. 1 (Augusta Road) enters the city of Lexington at forthcoming Morgan Drive. Downtown is two miles to the west.
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