U.S. 176 East - Sandy Run to Holly Hill

U.S. 176 (Old State Road) shifts east from the wye intersection with U.S. 21 (Columbia Road) to Sandy Run.
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Spanish Moss Drive (Road 212) connects U.S. 176 (Old State Road) with Branham Branch Road, 0.72 miles to the west.
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S.C. 6 (Caw Caw Highway) converges with U.S. 176 (Old State Road) 3.29 miles east of Interstate 26.
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S.C. 6 loops west to Swansea and north to Lexington, Lake Murray, and U.S. 76 at Ballentine.
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S.C. 6 accompanies U.S. 176 (Old State Road) southeast 0.76 miles ahead of the Calhoun County seat of St. Matthews.
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S.C. 6 branches east from U.S. 176 (Old State Road) along Bridge Street to the town of St. Matthews. Both routes meet U.S. 601 within the next 3.5 miles.
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Prior to construction in 2016, S.C. 6 separated from U.S. 176 (Old State Road) at a wye intersection.
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Burke Road (Road 22) extends 4.67 miles west from U.S. 176 at Chestnut Street to Interstate 26 at Exit 139.
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U.S. 176 (Old State Road) spans a Norfolk Southern Railroad ahead of U.S. 601 (St. Mathews Road) at Wertz Crossroads.
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U.S. 601 runs south from nearby St. Matthews to Orangeburg and South Carolina's LowCountry.
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North from St. Mathews, U.S. 601 continues to Wateree in eastern Richland County and Lugoff in Kershaw County.
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Reassurance marker posted south of Belleview Road (Road 45).
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Entering the small town of Cameron along U.S. 176 (Old State Road) eastbound.
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S.C. 33 (Cameron Road) meets U.S. 176 (Old State Road) in Cameron.
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S.C. 33 heads nrotheast to S.C. 267 near Lone Star and southwest to the South Carolina State University campus in Orangeburg.
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Flea Bite Creek flows west from U.S. 176 into Four Hole Swamp.
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U.S. 176 (Old State Road) crosses the Orangeburg County line just south of Farmers Road (Road 289).
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U.S. 301 (Five Chop Road) crosses paths with U.S. 176 (Old State Road) at Oaks Crossroads.
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U.S. 301 constitutes a four lane, divided highway west to I-26 en route to Orangeburg and east to I-95 by the town of Santee.
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