U.S. 301 South - Enfield to Sharpsburg

Entering the town of Enfield, U.S. 301/NC 481 follow McDaniel Street.
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NC 481 Business loops 1.71 miles west from U.S. 301/NC 481 (McDaniel Street) along Whitaker Street and Glenview Road to NC 481 outside Enfield.
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NC 481 angles northwest to NC 481 Business where it turns west to Interstate 95 at Exit 154.
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Crossing Fishing Creek, U.S. 301 proceeds south into Edgecombe County.
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Speights Chapel Road (SR 1409) branches southeast from U.S. 301 to Gethsemane ahead of this shield assembly posted near Bricks.
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Shifting west of a CSX Railroad line, U.S. 301 enters Nash County.
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NC 33 travels northwest from Tarboro and Leggett into the town of Whitakers along Main Street and Pippen Street.
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NC 33 extends southeast to Princeville, Greenville and Hobucken on Goose Creek Island near Pamlico Sound.
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NC 33 west joins U.S. 301 (S White Street) for 0.15 miles to W Nash Street.
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The town of Red Oak lies southwest beyond the end of NC 33 via Swift Creek Road (SR 1500) and Red Oak Road (SR 1003).
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NC 33 concludes 5.33 miles west of U.S. 301 in Whitakers to NC 4 and Swift Creek School Road (SR 1500) at Hickory.
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The traffic light at Johnston Road (SR 1516) serves the Cummins Rocky Mount Engine Plant south of Whitakers.
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Curving southwest into the city of Rocky Mount along Hathaway Street, U.S. 301 intersects Battleboro Avenue (SR 1560) in the former town of Battleboro.
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Downtown Rocky Mount lies eight miles further south of Battleboro via U.S. 301 and U.S. 301 Business.
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Red Oak Battleboro Road (SR 1524) provides a cut off from U.S. 301 onto NC 4 west.
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The roadways of U.S. 301 (Hathaway Street) diverge ahead of a wye interchange with NC 4.
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NC 4 travels 3.84 miles west to NC 48 at Interstate 95. The four lane highway was formerly part of Business Loop I-95.
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U.S. 301 proceeds south from NC 4 to intersect Belmont Lake Drive at the entrance to a Pfizer pharmaceutical plant.
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U.S. 301 south through Rocky Mount was part of Business Loop I-95 until 1988.
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Bishop Road (SR 1545) loops southwest from U.S. 301 to Thomas A. Betts Parkway (SR 1613).
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North Carolina Wesleyan University lines the west side of U.S. 301 south between Bishop Road and Thomas A. Betts Parkway.
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Thomas A. Betts Parkway (SR 1613) comprises an arterial bypass arcing southwest 5.40 miles to U.S. 64/Future I-87.
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U.S. 301 Business separates from U.S. 301 along N Church Street to Downtown Rocky Mount. The loop returns to U.S. 301 in 7.67 miles.
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U.S. 301 (N Wesleyan Boulevard) converges with NC 43/48 (Benvenue Road) at a parclo interchange by Golden East Crossing mall.
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NC 48 originates north of Downtown Rocky Mount from U.S. 301 Business along the couplet of Falls Road and Peachtree Street. NC 43 combines with NC 48 (Benvenue Road) north from U.S. 64/Future I-87.
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NC 43/48 part ways 0.61 miles north of U.S. 301. NC 43 continues northwest to Dortches and Red Oak while NC 48 turns north to Drake and Gold Rock.
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The fourth southbound lane along U.S. 301 (Wesleyan Boulevard) drops at the forthcoming parclo interchange with U.S. 64.
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Part of the Future I-87 corridor, U.S. 64 constitutes a freeway extending west from Rocky Mount to Raleigh and east to Tarboro and Williamston.
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A grade separation with Hunter Hill Road (SR 1604) precedes the westbound entrance ramp for U.S. 64 to Nashville, Zebulon and Raleigh.
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U.S. 64/Future I-87 connects with Interstate 95 at a cloverleaf interchange 3.6 miles to the west of U.S. 301 (Wesleyan Boulevard).
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Tarboro lies 17 miles to the east along U.S. 64/Future I-87. U.S. 64 concludes at Whale Bone Junction on the Outer Banks in 137 miles.
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U.S. 301 advances south from U.S. 64 to a parclo interchange with U.S. 64 Business (Sunset Avenue).
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U.S. 64 Business heads southeast across the Tar River to the couplet of Sunset Avenu east and Thomas Street west through Downtown Rocky Mount.
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U.S. 301 Business (S Church Street) returns to U.S. 301 from Rocky Mount at W Tarboro Road (SR 1006).
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Leading south from Rocky Mount, U.S. 301 enters the town of Sharpsburg along Hathaway Boulevard.
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