


Confirming marker posted south of U.S. 176 (Old State Road) on U.S. 601 (St. Mathews Road) at Wertz Crossroads.
11/21/21

U.S. 601 shifts east away from the parallel Norfolk Southern Railroad line into a six-ramp parclo interchange (Exit 145) with Interstate 26.
11/21/21

Addressing a weaving traffic pattern, loop ramps at the exchange joining I-26 with U.S. 601 were removed during construction from August 2016 to May 2017.
11/21/21

Commercial frontage lines U.S. 601 (St. Matthews Road) south from Interstate 26 to Orangeburg.
11/21/21

U.S. 601 (Magnolia Street) south meets U.S. 21/178 (Chestnut Street) at the north end of U.S. 21 Business. U.S. 21/178 encircle Orangeburg along an arterial bypass.
11/21/21

The truck route for U.S. 601 accompanies U.S. 21/178 (Chestnut Street) south to Charleston Highway and along S.C. 4 (Stonewall Jackson Boulevard) northwest back to U.S. 601.
11/21/21

U.S. 21 Business commences south alongside U.S. 601 (Magnolia Street) toward Downtown Orangeburg. The bannered route run 2.73 miles south to U.S. 21 at Rowesville Road.
11/21/21



U.S. 21 Business is not acknowledged on the succeeding confirming marker south on Magnolia Street.
11/21/21

Continuing beyond Claflin University, U.S. 601/21 Business (Magnolia Street) meet S.C. 33 (Russell Street) east of Downtown Orangeburg.
11/21/21

S.C. 33 south passes through Downtown west to U.S. 301/601 by the North Fork of the Edisto River. S.C. 33 north heads to South Carolina State University and Cameron.
11/21/21
Photo Credits:
11/21/21 by AARoads
Connect with:
Interstate 26
U.S. 21
U.S. 176
U.S. 178
U.S. 301
Highway 33
Page Updated 03-10-2022.