
East
SR 16 stems east from SR 121 and East Raiford two miles to the Florida State Prison complex. There are no shields posted eastbound in Union County.
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Union County Road 199 follows a stair stepped route 4.08 miles north from SR 16 to CR 125.
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Curving southeast, SR 16 crosses the New River into Bradford County.
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CR 225 constitutes a 12.20 mile long loop from SR 16 south to SR 100, west of Starke, and east to U.S. 301 in Lawtey.
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The eastern branch of CR 255 runs southeast from Lawtey to SR 16 near Kingsley Lake.
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CR 229A links SR 16 at Heilbronn with CR 229, 2.29 miles to the west.
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Confirming marker posted southeast of CR 233.
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SR 16 enters a diamond interchange with U.S. 301 ALT (Starke Truck Route) just south of NW 17thh Street.
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A 6.43 mile long freeway, U.S. 301 ALT bypasses Starke.
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The Starke Truck Route was constructed from August 2016 to September 2019.
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The exchange joining SR 16 with U.S. 301 ALT lies along the Starke city line. SR 16 (Raiford Road) fully enters the Bradford County seat beyond NW 173rd street.
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SR 16 (Brownlee Street) curves southeast into the Starke street grid from CR 229 (Weldon Street).
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SR 16 proceeds east to the commercial strip along U.S. 301 (Temple Avenue).
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U.S. 301 travels northeast from Starke to Lawtey and Maxville in Jacksonville and south to Hampton, Waldo and Ocala.
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SR 16 east enters Clay County 3.70 miles from U.S. 301 (Temple Avenue) in Starke.
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Continuing east into Camp Blanding, SR 16 converges with the east end of SR 230 by Kingsley Lake. SR 230S links SR 16 east with SR 230 leading south to the West Gate of Camp Blanding and west back to Starke.
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Turning north at Kingsley Village, SR 16 overtakes SR 230 east at a wye intersection.
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SR 16 heads north from the east end of SR 230 around Kingsley Lake.
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Kingsley Lake Drive (unsigned CR 16A) branches east from SR 16 closer to Kingsley Lake. This guide sign was removed by 2009.
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CR 225 runs 6.43 miles southeast from U.S. 301 in Lawtey to SR 16 near Kingsley Lake.
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Avenue A stems south from SR 16, just east of Kingsley Lake Road, to the main gate into Camp Blanding.
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CR 215 provides a cut off from SR 16 east to SR 21 north into Middleburg.
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Leading away from SR 21 on SR 16 eastbound.
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SR 16 across the town of Penney Farms is James C. Penney Memorial Boulevard.
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The east end of CR 218 ties into SR 16 at Polling Boulevard in Penney Farms.
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CR 218 arcs 20.39 miles northwest to Middleburg and U.S. 301 near Maxville in Jacksonville.
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07/28/18
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SR 16 expands to four lanes through the diverging diamond interchange (DDI) with the First Coast Expressway (SR 23).
08/12/25
The First Coast Expressway opened between SR 21 (Blanding Boulevard) and U.S. 17 south of Green Cove Springs on August 9, 2025. The entrance ramp to SR 23 south from SR 16 did not open at that time due to ongoing construction.
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SR 23 (First Coast Expressway) joins Green Cove Springs with Interstate 10 west of Whitehouse in Jacksonville.
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CR 315 (Springpark Road) loops southwest from SR 16 to Saunders and Hogarth Roads, and along unpaved Sharron Road west to SR 21.
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4.18 miles in length, the northern leg of CR 315 circumvents Green Cove Springs between SR 16 and U.S. 17.
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CR 16A comprises a residential loop south from SR 16 beyond Clay High School.
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CR 315A angles 1.1 miles northwest from SR 16 to CR 315 at Rosemary Hill Road.
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CR 16A also loops north from SR 16 along Randall Road.
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Page Updated Wednesday August 13, 2025.