U.S. 421

U.S. 421

U.S. 421 crosses Southwestern Virginia 68.98 miles west from Bristol to the Tennessee Valley Divide north of Stone Mountain. The majority of U.S. 421 within the Old Dominion overlaps with other routes.

U.S. 421 Virginia Guides

Within Bristol, U.S. 421 enters the state alongside U.S. 11E/19 (Commonwealth Avenue) north for 0.58 miles to U.S. 11W (Euclid Avenue). U.S. 11W/421 combine southwest 1.12 miles back to the state line, where U.S. 421 shifts onto Gate City Highway. U.S. 421 continues 1.20 miles along Gate City Highway to I-81, where U.S. 58 joins the highway west to U.S. 23 at Gate City.

Prior to 2011, U.S. 421 in Bristol followed a circuitous route north from Anderson Street in Tennessee to U.S. 11E/19 along Commonwealth Avenue in Virginia. Approved by the American Association of State Highway and Transportation Officials (AASHTO) on May 2, 2011, U.S. 421 was relocated off Martin Luther King, Jr. Boulevard north, Cumberland Street west, Piedmont Avenue south and Goode Street west to meet U.S. 11/19 (Volunteer Parkway) directly from Anderson Street. Good, Piedmont and Cumberland remain a part of U.S. 11-19 Truck, which follow MLK Boulevard northeast to Moore Street.

U.S. 23 joins U.S. 58/421 west from Gate City to Clinchport and Duffield. U.S. 58/421 continue across Powell Mountain to Stickleyville in Lee County. The two part ways north of Wallen Ridge at Dot. The remaining 13.11 miles of U.S. 421 head north to Woodway and Pennington Gap and west from Stone Creek to the Kentucky state line.

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Page Updated Monday August 09, 2021.