U.S. 6 travels across the city of Omaha from 204th Street at Elkhorn east to Downtown. The route travels north from the city of Gretna, straddling western fringes of the Omaha suburbs to a diamond interchange with U.S. 275/N-92 (Center Road). Two miles north from there, U.S. 6 overtakes L-28B along the West Dodge Expressway, a well traveled commuter freeway and commercial corridor leading east to I-680 at Westroads Mall.
West Dodge Road transitions into an eight-lane arterial leading east from N 96th Street. U.S. 6 shifts southward from Cass Street to cross Little Papillion Creek into a sprawling retail area anchored by Crossroads Mall. East between Elmwood Park and the Fairacres neighborhoods, U.S. 6 narrows into a five-lane boulevard, with lane control signals adjusting the center lane as a third lane for U.S. 6 east or west.
Passing north along the University of Nebraska Omaha (UNO) campus, U.S. 6 (Dodge Street) advances through the Dundee-Memorial Park neighborhood area. The five lane boulevard separates into a one-way couplet at N 31st Street. U.S. 6 east follows Douglas Street one block south of westbound Dodge Street through Downtown Omaha and Downtown Northeast.
U.S. 6 accompanies Interstate 480 (Gerald Ford Freeway) across the Missouri River into Council Bluffs, Iowa, where it combines with I-29 south. The US highway formerly extended east from the freeway end at I-29 onto Broadway, a five-lane commercial boulevard heading to the Council Bluffs city center. U.S. 6 then shifted northeast along Kanesville Boulevard, a divided arterial, to Interstate 80 at Exit 8.
Through the Omaha, U.S. 6 has always traveled along Dodge Street. It was cosigned with U.S. 30 Alternate east from its shared alignment with N-92 to North Broadway. Prior to construction of the I-480 bridge, the Ak-Sar-Ben Bridge (Nebraska spelled backwards), carried U.S. 6 east to Broadway in Council Bluffs. Broadway, Pierce Street and McPherson Avenue represent the historic alignment bypassed by Kanesville Boulevard.
Iowa petitioned AASHTO to relocate U.S. 6 off Broadway through Council Bluffs on May 25, 2016. Approved with a condition, the realignment takes U.S. 6 south along I-29 from I-480 to I-80, and east along I-80 to the Kanesville Boulevard interchange (Exit 8). The relinquishment allowed the city of Council Bluffs to redesign Broadway.